Unmet needs in CCA — 1 of 3

Diagnosis of CCA presents significant clinical challenges

CCA is usually asymptomatic in its early stages, often resulting in late diagnosis when patients are already at an advanced stage7,10

20–25%

of iCCA cases are diagnosed because of an incidental finding, owing to non-specific symptoms7,11

90%

of patients with eCCA present with painless jaundice; 10% present with acute cholangitis5,10

Lack of absolute diagnostic criteria and low specificity of diagnostic modalities make diagnosis of CCA difficult7,8,10

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What are the symptoms of advanced CCA?