PEMAZYRE dosing and administration — 4 of 5
Dose modifications for PEMAZYRE (1/2)
Dose modifications may be needed in cases of hyperphosphataemia and serous retinal detachment1
>5.5 – ≤7 mg/dL
>7 – ≤10 mg/dL
PEMAZYRE if levels do not return to <7 mg/dL within 2 weeks of starting a phosphate-lowering therapy
PEMAZYRE and phosphate-lowering therapy at the same dose when level returns to <7 mg/dL
Upon recurrence of serum phosphate at >7 mg/dL with phosphate-lowering therapy, reduce PEMAZYRE 1 dose level
PEMAZYRE if levels continue >10 mg/dL for 1 week
PEMAZYRE and phosphate-lowering therapy 1 dose level lower when serum phosphate is <7 mg/dL
If there is a recurrence of serum phosphate >10 mg/dL following 2 dose reductions, permanently discontinue
- Swiss Professional Information PEMAZYRE® (pemigatinib) on www.swissmedicinfo.ch.
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All references are available upon request
Abbreviated Prescribing Information
▼ This medicinal product is subject to additional monitoring. For further information, see product information Pemazyre on www.swissmedicinfo.ch.
Revision date: January 2023. Marketing authorisation holder: Incyte Biosciences International Sàrl, CH-1110 Morges. Refer to www.swissmedicinfo.ch for detailed information.
Resources and support
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